NAD+ peptides

Description

Product Overview
NAD⁺ Supplement – 500 mg

NAD⁺ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in all living cells. Structurally composed of nicotinamide, adenine, ribose sugars, and phosphate groups, it functions as a key redox carrier—cycling between its oxidized (NAD⁺) and reduced (NADH) states to support vital metabolic reactions. This product is provided as a high-purity, research-grade 500 mg powder intended strictly for laboratory use in studies related to cellular metabolism, redox balance, and enzymatic activity. It is not intended for medical or therapeutic use.

Research Applications and Areas of Interest

1. Metabolic Regulation
NAD⁺ plays a crucial role in core metabolic pathways such as glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative phosphorylation. Acting as an electron acceptor, it facilitates intracellular energy transfer. Researchers often use NAD⁺ supplementation in experimental models to evaluate metabolic flux, energy production, and redox balance under controlled conditions.

2. Enzyme–Cofactor Interactions
NAD⁺ serves as a cofactor for a wide range of enzymes, including sirtuins, dehydrogenases, and PARPs (poly ADP-ribose polymerases). These enzymes are involved in processes such as DNA repair, chromatin remodeling, and protein modification. Laboratory studies use NAD⁺ to examine enzyme activity, binding interactions, and biochemical pathways in controlled systems.

3. Redox Balance and ROS Signaling
Within redox biology, NAD⁺ is widely used to investigate cellular responses to oxidative stress and reactive oxygen species (ROS). By adjusting NAD⁺ levels, researchers can study antioxidant defenses, redox-sensitive signaling pathways, and mitochondrial responses in models of oxidative imbalance.

4. Neuroscience Research
NAD⁺ is increasingly explored in studies of neuronal metabolism and neuroprotection. It is used in neuronal cultures and ex vivo systems to better understand its role in maintaining mitochondrial function, synaptic activity, and cellular signaling, particularly under stress conditions.

5. Cellular Aging and Longevity Models
Due to its involvement in metabolic stability and genomic maintenance, NAD⁺ is commonly studied in models of cellular aging and senescence. Researchers use it to observe changes in energy metabolism, stress resilience, and sirtuin activity in aging or stress-induced cell systems.

Summary

NAD⁺ (500 mg) provides a high-purity option for laboratory research across fields such as metabolism, enzymology, redox biology, and neuroscience. Its broad biological relevance makes it a key compound in studies focused on energy production, oxidative regulation, and cellular stability. This product is supplied as a powder and is strictly designated for research purposes only—not for human or veterinary use.

Technical Specifications

• Synonyms: Nicotinamide Adenine Dinucleotide (oxidized form), NAD⁺
• IUPAC Name: β-Nicotinamide adenine dinucleotide
• Molecular Formula: C₂₁H₂₇N₇O₁₄P
• Molecular Weight: 663.43 g/mol
• CAS Number: 53-84-9
• PubChem CID: 439174

Related Research Peptides

Researchers working with NAD⁺ may also investigate complementary peptides involved in mitochondrial function, oxidative stress, and cellular aging:

• SS-31 (10 mg): A mitochondria-targeted peptide studied for its role in improving bioenergetics and reducing oxidative stress.
• Epitalon (10 mg): Commonly researched in longevity and aging models, including telomere-related studies.
• KPV (5 mg): A tripeptide frequently explored in inflammation and immune response research connected to oxidative pathways.

Storage and Handling

• Store lyophilized powder at -20 °C in a dry environment
• After reconstitution, aliquot to prevent repeated freeze-thaw cycles
• Reconstituted solution may be stored at 4 °C for a limited time
• Stable until expiry when stored properly at -20 °C

Additional Information

• Source: Biosynthetic
• Reconstitution: Use bacteriostatic water
• Usage: Strictly for laboratory research and educational purposes only
• Intended for use by licensed researchers only

Images are for illustrative purposes only.